The listing is categorized by type of rna trna rrna mrna snrna and other rnas a total of 93 different modified nucleosides have been reported in rna with the largest number and greatest structural diversity in trna 79 and 28 in rrna 12 in mrna 11 in snrna and 3 in other small rnas. The modified nucleosides in nucleic acids hall ross hume isbn 9780231030182 kostenloser versand fur alle bucher mit versand und verkauf duch amazon. The modified nucleosides in nucleic acids this edition was published in 1971 by columbia university press in new york edition notes bibliography p 413 435 classifications dewey decimal class 5748 732 library of congress qp801n8 h3 the physical object pagination xii 451 p number of pages 451 id numbers . In one embodiment the modified nucleosides modified nucleotides and modified nucleic acids can be chemically modified on the major groove face thereby disrupting major groove binding partner interactions which may cause innate immune responses further these modified nucleosides modified nucleotides and modified nucleic acids can be used to deliver a payload eg detectable or therapeutic agent to a biological target for example the nucleic acids can be covalently linked to a
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